Can Humans Live Beyond 122? The Search for Longevity’s Edge

What is the absolute limit of the human lifespan? While Jeanne Calment’s record of 122 years and 164 days still stands since 1997, it’s still a mystery whether humans could potentially live even longer.

With Tomiko Itooka of Japan currently holding the title of the world’s oldest living person at 116 and an estimated 300,000 people projected to reach age 110 by 2080, understanding the boundaries of human longevity has never been more relevant.

The Current State of Supercentenarians

Can Humans Live Beyond 122? The Search for Longevity’s Edge » group of supercentenarian dp742689630 dnoh
Image Credit: PeopleImages.com/Deposit Photos

Today’s population of supercentenarians—people who live beyond 110 years—represents an elite group of survivors who typically live free of significant age-related diseases until shortly before death. Current estimates suggest there are between 150 and 600 living supercentenarians worldwide.

Japan leads in longevity statistics, with multiple individuals over 113 years old currently living there. These exceptional individuals often share common characteristics, including delayed onset of age-related diseases and maintained functional independence well past 100 years.

Scientific Predictions & Probability

Can Humans Live Beyond 122? The Search for Longevity’s Edge » caregiver with old woman ss2462286915
Image Credit: Pixel-Shot/Shutterstock

Research indicates an 89% chance that someone will live to at least 126 years during this century, though the probability drops dramatically for higher ages. (ref)

However, scientists have observed a deceleration in life expectancy improvements, particularly in nations with the longest-living populations. Current projections suggest that maximum life expectancy will settle around 87 years—approximately 84 for males and 90 for females.

Biological Factors & Genetics

Can Humans Live Beyond 122? The Search for Longevity’s Edge » genetic ss1968508504
Image Credit: Natali _ Mis/Shutterstock

DNA repair capability emerges as a crucial factor in determining maximum lifespan. Studies of centenarians reveal that their cells possess characteristics typical of younger individuals, particularly in DNA repair mechanisms. 

Twin studies suggest that approximately 25% of lifespan variation is attributable to genetics, with the remainder influenced by environmental factors and lifestyle choices. (ref)

Environmental Influences & Health Disparities

Can Humans Live Beyond 122? The Search for Longevity’s Edge » old woman drinking tea dp275663152 dnoh
Image Credit: dimaberkut/Deposit Photos

Environmental factors significantly impact longevity potential. Research indicates that environmental degradation poses a serious threat to life expectancy.

Air pollution alone caused 4.2 million premature deaths in 2019, with nine out of ten people worldwide residing in areas with hazardous air quality. (ref)

Studies have shown that atmospheric pressure, temperature, and humidity play crucial roles in longevity, with men living longer in areas with low atmospheric pressure and women showing increased longevity in regions with higher temperatures.

Gender Differences in Longevity

Can Humans Live Beyond 122? The Search for Longevity’s Edge » old couple on phone ss2252992161
Image Credit: Perfect Wave/Shutterstock.

Research consistently shows that women outlive men across all age groups. In the United States, women’s life expectancy is 81.2 years compared to 76.4 years for men. (ref)

This significant disparity is partly attributed to men’s tendency toward riskier behaviors and lifestyle choices that may result in fatal accidents.

The Reality of Limits

Can Humans Live Beyond 122? The Search for Longevity’s Edge » old woman watching dp549152636 dnoh
Image Credit: marcoscasiano/Deposit Photos

Despite technological advances, evidence suggests we’re approaching natural limits to human longevity. Even in a hypothetical scenario where all deaths before age 50 were eliminated, the maximum increase in life expectancy would only be about 1.5 years. 

In 2019, only about 2% of Americans reached age 100, compared to approximately 5% in Japan and 9% in Hong Kong. (ref)

Future Prospects

Can Humans Live Beyond 122? The Search for Longevity’s Edge » woman with number age wc
Image Credit: John Michael Berry, CC BY-SA 4.0, via Wikimedia Commons

While the number of centenarians continues to grow due to population increase, reaching extreme ages remains rare. Current data suggests that fewer than 15% of women and 5% of men are likely to reach age 100 in most countries. 

However, researchers note interesting patterns in mortality rates at extreme ages, with some evidence of mortality plateaus—periods where death rates cease to increase with age.

While we may not achieve immortality, understanding these limits helps focus research on extending not just lifespan, but the quality of life in our later years.

Source:

  1. National Library of Medicine
Nancy Maffia » nancy
Nancy Maffia
Author & Editor | + posts

Nancy received a bachelor’s in biology from Elmira College and a master’s degree in horticulture and communications from the University of Kentucky. Worked in plant taxonomy at the University of Florida and the L. H. Bailey Hortorium at Cornell University, and wrote and edited gardening books at Rodale Press in Emmaus, PA. Her interests are plant identification, gardening, hiking, and reading.