Scientists Find Surprising Differences in the Blood of People Who Live Past 90

Centenarians, individuals who live to be 100 years old or more, have experienced a remarkable surge in numbers, doubling approximately every decade since the 1950s.1 

This unprecedented growth has made them the fastest-growing demographic group globally. By 2050, the global population of centenarians is projected to reach 3.7 million.2 

This growth sparked widespread interest in understanding the factors that contribute to their longevity.

Ancient Roots of Longevity Research

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The quest to understand the factors influencing a long and healthy life is not new. Even ancient philosophers like Aristotle and Plato had theoretical interests on aging over 2,300 years ago.(ref) 

Their writings laid the foundation for the ongoing exploration of this complex topic, which continues to captivate scientists and society alike.

Biomarker Clues to Exceptional Longevity

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In a study published in GeroScience, researchers identified common biomarkers associated with exceptional longevity. By comparing biomarker profiles of individuals who lived past 90 with those of their shorter-lived peers, the study shed light on potential indicators of a long and healthy life.

Among the key findings were lower levels of glucose, creatinine (linked to kidney function), and uric acid (a waste product from food digestion) in centenarians. These findings suggest a potential link between metabolic health, nutrition, and exceptional longevity.(ref)

Centenarian Study

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The study, one of the largest of its kind, involved data from 44,000 Swedes who underwent health assessments between the ages of 64 and 99. 

The participants were followed for up to 35 years through Swedish register data, with 2.7 percent (1,224) reaching the age of 100. Notably, 85 percent of the centenarians were female.

Lifestyle & Longevity

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While the study did not allow for definitive conclusions regarding lifestyle factors, the authors acknowledged the likely influence of nutrition and alcohol intake on longevity.

Further research is needed to explore the specific impact of these and other lifestyle choices on lifespan and overall health.

Genetics, Lifestyle & Chance

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The observation of biomarker differences long before death suggests that both genetics and lifestyle determine longevity. 

However, chance and other unknown factors also contribute to the lifespan.(ref) Understanding the relative contributions of these factors remains a challenge for ongoing research. 

Source:

  1. GeroScience
  2. Pew Research Center
Martha A. Lavallie
Martha A. Lavallie
Author & Editor | + posts

Martha is a journalist with close to a decade of experience in uncovering and reporting on the most compelling stories of our time. Passionate about staying ahead of the curve, she specializes in shedding light on trending topics and captivating global narratives. Her insightful articles have garnered acclaim, making her a trusted voice in today's dynamic media landscape.